Modified Acyl-ACP desaturase
US5888790A · kind A · utility
12Cited by
4References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 9, 1997 |
| Grant date | Mar 30, 1999 |
| Priority date | — |
| Expiry date | May 9, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed is a method for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.