Patent · US Expired

Combination reagent holding and test device

US5888826A · kind A · utility

72Cited by
46References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 25, 1997
Grant dateMar 30, 1999
Priority date
Expiry dateNov 25, 2017

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2035/00148
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present invention provides novel test cartridges for use in the assay of liquid samples and methods of carrying out such assays. These test cartridges are particularly useful in assays which include at least one step during which the sample to be assayed and one or more components of the assay system are kept separated by a pierceable member. The test cartridges comprise a housing through which the sample flows during the assay. The housing includes a holding chamber for holding the sample and a test chamber separated by a pierceable member having a cut therein. The test chamber further includes a partition member which has an opening therethrough and includes at least one reagent for the assay. A transfer member movably mounted in the test chamber can move towards and pierce the pierceable member by moving through the cut and contact the liquid sample in the holding chamber. When the transfer member has been moved towards and pierces the pierceable member to contact the liquid sample and a negative pressure is created in the test chamber, liquid sample moves through the transfer member, into the test chamber and through the opening in the partition member.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.