Photolabile caged ionophores and method of using in a membrane separation process
US5888829A · kind A · utility
10Cited by
9References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 26, 1996 |
| Grant date | Mar 30, 1999 |
| Priority date | — |
| Expiry date | Apr 26, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes a family of photolabile caged ionophores. The compounds of the present invention are photolytically cleavable esters of nigericin, ionomycin, A-23187, 4-Br-A-23187 and monensin. The photolysis of the present compounds allows the release of the free ionophore in vivo or in vitro with precise spatial and temporal control. The compounds are useful in the study of ion transport and control in cells and across membranes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.