Dihydropyrimidone derivatives as NPY antagonists
US5889016A · kind A · utility
12Cited by
3References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 20, 1998 |
| Grant date | Mar 30, 1999 |
| Priority date | — |
| Expiry date | Jan 20, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a series of non-peptidergic antagonists of NPY comprising piperidine derivatives of 4-phenyl-1,4-dihydropyrimidinones of the Formula I ##STR1## wherein R, R.sup.1 and R.sup.2 are defined herein. As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.