Method for stabilizing pranoprofen and stable liquid preparation of pranaprofen
US5889030A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Jun 12, 1997 |
| Grant date | Mar 30, 1999 |
| Priority date | — |
| Expiry date | Jun 12, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/1393
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for stabilizing pranoprofen, comprising placing an aqueous solution of pranoprofen in coexistence with an antioxidant, or placing an aqueous solution of pranoprofen under the conditions of limited supply of oxygen, and a stable aqueous preparation of pranoprofen, comprising pranoprofen and an antioxidant. According to the present invention, the decomposition of pranoprofen in an aqueous solution of pranoprofen is remarkably suppressed. In particular, pranoprofen becomes stable to light, thus permitting long-term preservation of an aqueous solution, specifically a liquid preparation, of pranoprofen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.