Patent · US Expired

Stabilization of prostaglandin drug

US5889051A · kind A · utility

22Cited by
3References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 15, 1997
Grant dateMar 30, 1999
Priority date
Expiry dateJul 15, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/146
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A stable solid dispersion of prostaglandin drug, particularly Misoprostol, (.+-.)methyl 7-3(.alpha.)-hydroxy-2-.beta.-(4 (RS)-4-hydroxy-4-methyl-trans-1-octen-1-yl)-oxycyclopent-1.alpha.-yl!hepta noate, comprising ammonio methacrylate copolymers. The ammonio methacrylate copolymers comprise Eudragit RS series, Eudragit RL series, Eudragit S, Eudragit L, and the mixture thereof. The stable solid dispersion is a sustained release type.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.