Synthetic glucagon binding proteins
US5889167A · kind A · utility
7Cited by
0References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 21, 1997 |
| Grant date | Mar 30, 1999 |
| Priority date | — |
| Expiry date | May 21, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/605
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A synthetic human glucagon (hGlu) binding protein designated hGlu.DELTA.252-259 binding protein is cloned, expressed and used in an in vitro assay to screen for compounds that bind to the synthetic binding protein, including compounds that specifically stimulate or inhibit the binding of glucagon to the synthetic receptor. The invention includes the assay, the synthetic binding protein used in the assay, DNA encoding the synthetic binding protein, cells expressing the synthetic binding protein, and compounds identified through the use of the synthetic binding protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.