Antigen associated with type I diabetes mellitus
US5891437A · kind A · utility
10Cited by
6References
16Claims
0Family size
Inventors
Key dates
| Filing date | Sep 16, 1994 |
| Grant date | Apr 6, 1999 |
| Priority date | — |
| Expiry date | Sep 16, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/81
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A 69 kD protein, designated PM-1, is expressed in human pancreatic islet cells and a human insulinoma. The amino acid sequence of the protein has been determined. Autoantibodies to the PM-1 protein have been found in sera of prediabetic patients. Natural, synthetic or recombinant forms of the PM-1 protein can be used in immunochemical assays to detect anti-PM-1-autoantibodies and to identify patients at risk of developing diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.