System and method for mapping the distribution of normal and abnormal cells in sections of tissue
US5891619A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 14, 1997 |
| Grant date | Apr 6, 1999 |
| Priority date | — |
| Expiry date | Jan 14, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01J3/44
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system and method is described for permitting the simultaneous automated collection of data with regard to the presence of diseased cells, in particular neo-plastic, dysplastic or cancerous cells, or normal cells at a given site in a section of tissue. This is accomplished according to the following steps. First, IR spectral data are collected simultaneously for each cell or pixel of the tissue. Next, these data are analyzed by identifying the cell types encountered in the sample by comparing them with reference data sets for healthy and diseased cells. Finally, a false color mapping of the distribution of different types of cells in the tissue section is presented that permits assessment of the prevalence of diseased cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.