Peptide derived from human immunodeficiency virus type 1 (HIV-1), isolate ant70, containing an immunodominant epitope and it's use in immunodiagnostic assays
US5891640A · kind A · utility
13Cited by
2References
9Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 22, 1993 |
| Grant date | Apr 6, 1999 |
| Priority date | — |
| Expiry date | Nov 22, 2013 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/18
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention is directed toward a peptide corresponding to an immunologically important viral epitope. Specifically, the peptide corresponds to an immunodominant epitope identified in the gp41 region of the human immunodeficiency virus type 1 (HIV-1), strain Ant70. This peptide has the following amino acid sequence: NH.sub.2 -Leu-Trp-Gly-Cys-Lys-Gly-Lys-Leu-Val-Cys-CO.sub.2 H. The invention also relates to the use of this peptide, particularly when biotinylated in the form of complexes of streptavidin-biotinylated peptides or of avidin-biotinylated peptides, for the in vitro determination of HIV-1-specific antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.