Method for producing ester of (S)-.gamma.-halogenated-.beta.-hydroxybutyric acid
US5891685A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 3, 1997 |
| Grant date | Apr 6, 1999 |
| Priority date | — |
| Expiry date | Jun 3, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/62
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Microbial cells and/or a preparation thereof of a microorganism is allowed to act on ester of .gamma.-halogenated-acetoacetic acid, and its carbonyl group at .beta.-position is stereospecifically reduced to produce ester of (S)-.gamma.-halogenated-.beta.-hydroxybutyric acid in a short period of time at a highly accumulated degree and at a high yield, the microorganism being selected from the group consisting of those belonging to the genera Phoma, Nectria, Pseudonectria, Spondylocladium, Melanospora, Metarhizium, Gliocladium, Pestalotia, Pestalotiopsis, Curvularia, Hormonema, Sydowia, Sarcinomyces, Dothiora, Xanthothecium, Dothidea, Pringsheimia, and Selenophoma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.