Method of production of poly-.beta.-hydroxyalkanoate copolymers
US5891686A · kind A · utility
9Cited by
19References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 24, 1997 |
| Grant date | Apr 6, 1999 |
| Priority date | — |
| Expiry date | Jun 24, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/625
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods for the production of poly-.beta.-hydroxyalkanoate copolymer comprising the steps of (a) introducing into a prokaryotic host cell a vector construct which directs the expression of a sequence which encodes a poly-.beta.-hydroxybutyrate biosynthetic pathway, (b) introducing into the host cell a vector construct which directs the expression of one or more proteins which regulate acetate and propionate metabolism, (c) culturing the host cell in medium containing propionate or a derivative thereof, and (d) isolating poly-.beta.-hydroxyalkanoate copolymer from the cultured host cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.