Use of R-(Z)!-.alpha.-(methoxyimino)-.alpha.-(1-azabicyclo 2.2.2.!oct-3-yl)acetonitrile to reduce amyloid .beta.A4 formation in alzheimer's disease
US5891887A · kind A · utility
2Cited by
3References
4Claims
0Family size
Inventors
Key dates
| Filing date | Apr 25, 1997 |
| Grant date | Apr 6, 1999 |
| Priority date | — |
| Expiry date | Apr 25, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of enhancing amyloid precursor protein processing along a non-amyloidogenic pathway in patients suffering from, or at risk of developing, Alzheimer's disease and a method of treatment or prophylaxis of Alzheimer's disease by reducing .beta.A4 production in patients suffering from, or at risk of developing, Alzheimer's disease comprising administering to the patient an effective, non-toxic amount of an acetonitrile compound, use of the compound in preparation of a medicament for use in the method and a composition for use in the method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.