Inhibitors of farnesyl-protein transferase
US5891889A · kind A · utility
70Cited by
7References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 1, 1997 |
| Grant date | Apr 6, 1999 |
| Priority date | — |
| Expiry date | Apr 1, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.