Method for treating or preventing ulcerative diseases by administering thia- or oxazolidinone compounds
US5891898A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 25, 1998 |
| Grant date | Apr 6, 1999 |
| Priority date | — |
| Expiry date | Aug 25, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for the treatment or prevention of an ulcerative disease comprising administering to a patient an effective amount of an active compound in admixture with a pharmacologically acceptable carrier or diluent, wherein said active compound is a thia-or oxazolidinone compound of the following formula or a pharmacologically acceptable salt thereof: ##STR1## wherein W is sulfur or oxygen and X is --N(R.sup.3)--, or X is sulfur or oxygen and W is --N(R.sup.3)--; R.sup.3 is hydrogen, C.sub.1 -C.sub.6 alkyl or aralkyl; R.sup.4 and R.sup.5 are the same or different and each is hydrogen, C.sub.1 -C.sub.6 alkyl,aralkyl, aryl, 5- or 6-membered aromatic heterocyclic; R.sup.6 is hydrogen, C.sub.1 -C.sub.6 alkyl or aralkyl; and A is C.sub.2 -C.sub.6 alkylene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.