Amidinohydrazones as protease inhibitors
US5891909A · kind A · utility
28Cited by
10References
76Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 27, 1997 |
| Grant date | Apr 6, 1999 |
| Priority date | — |
| Expiry date | Mar 27, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Amidino and benzamidino compounds, including compounds of the formula: ##STR1## wherein R.sup.1 -R.sup.4, R.sup.6 -R.sup.9, Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit proteolytic enzymes such as thrombin are described. Also described are methods for preparing the compounds of Formula I.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.