Patent · US Expired

Method and construct for producing graft tissue from extracellular matrix

US5893888A · kind A · utility

61Cited by
23References
10Claims
0Family size

Assignee

Inventor

Key dates

Filing dateSep 6, 1994
Grant dateApr 13, 1999
Priority date
Expiry dateSep 6, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2533/90
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

Using connective tissues as starting materials, a method is described for producing matrix particulates. The invention includes an embodiment wherein the matrix particulate are seeded with living human cells or with cells of other species. Further, the invention encompasses fusing the particulates to constitute composites of various shapes, or holding them together in a porous container made of membranous biopolymers. The particulates or composites can be used as tissues for grafting or as model systems for research and testing. The invention also encompasses the spinning of threads in which the matrix particulates are components.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.