Crystallization of proteins
US5898067A · kind A · utility
37Cited by
9References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 2, 1998 |
| Grant date | Apr 27, 1999 |
| Priority date | — |
| Expiry date | Feb 2, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/32
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of providing zinc containing crystals of a protein derivative which has a lysine residue which carries a lipophilic substituent on the .epsilon.-amino group, said method comprising providing a solution of the protein derivative in an alkaline buffer, which further contains a zinc salt, adjusting the pH value of the solution to a value between 7 and 10, and isolating the crystals formed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.