Patent · US Expired

Compliant tissue sealants

US5900245A · kind A · utility

361Cited by
49References
37Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 23, 1996
Grant dateMay 4, 1999
Priority date
Expiry dateSep 23, 2016

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/1635
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An improved barrier or drug delivery system which is highly adherent to the surface to which it is applied is disclosed, along with methods for making the barrier. In the preferred embodiment, the system is compliant, in that it is capable of conforming to the three dimensional structure of a tissue surface as the tissue bends and deforms during healing processes. The barrier or drug delivery systems is formed as a polymeric coating on tissue surfaces by applied a polymerizable monomer to the surface, and then polymerizing the monomer. The polymerized compliant coating preferably is biodegradable and biocompatible, and can be designed with selected properties of compliancy and elasticity for different surgical and therapeutic applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.