Method of reducing side effects associated with administration of oxygen-carrying proteins
US5900402A · kind A · utility
14Cited by
12References
43Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 29, 1997 |
| Grant date | May 4, 1999 |
| Priority date | — |
| Expiry date | May 29, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of reducing side-effects associated with administering oxygen-carrying proteins to mammals is disclosed. The method includes: PA1 a) reacting an oxygen-carrying protein with a substantially non-antigenic polymer to form a oxygen-carrying protein-substantially non-antigenic polymer conjugate; and PA1 b) administering the oxygen-carrying protein-substantially non-antigenic polymer conjugate to a mammal in need of the oxygen-carrying protein. Preferred oxygen-carrying proteins include recombinantly prepared hemoglobins and preferred non-antigenic polymers include polyethylene glycol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.