N-heteroarenesulfonyl-protected amino acid reagents for peptide synthesis
US5900427A · kind A · utility
4Cited by
9References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 3, 1996 |
| Grant date | May 4, 1999 |
| Priority date | — |
| Expiry date | May 3, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to the use of heteroarenesulfonyl groups as protecting groups for amino groups, particularly the amino groups of amino acids, and specifically to nitrogen-protected (N-protected) amino acid reagents, which are particularly well-suited for use in peptide syntheses. In particular, the N-protected amino acid reagent is an N-heteroarenesulfonyl-protected amino acid halide. The heteroarenesulfonyl protecting groups are readily removed under relatively mild conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.