Bead linkers for immobilizing nucleic acids to solid supports
US5900481A · kind A · utility
579Cited by
6References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 6, 1996 |
| Grant date | May 4, 1999 |
| Priority date | — |
| Expiry date | Nov 6, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/1069
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Novel compositions comprised of at least one bead conjugated to a solid support and further conjugated to at least one nucleic acid and preferred methods for making the novel compositions are described. As compared to "flat" surfaces, beads linked to a solid support provide an increased surface area for immobilization of nucleic acids. Furthermore, by selecting a bead with the desired functionality, a practitioner can select a functionalization chemistry for immobilizing nucleic acids, which is different from the chemistry of the solid support.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.