Solid and liquid solutions of sparingly water-soluble medicinal substances

US5902606A · kind A · utility

Assignee

• ALFATEC-Pharm GmbH · DE

Inventors

• Jens-Christian Wunderlich · Heidelberg, DE
• Ursula Schick · Schriesheim, DE
• Jurgen Werry · Ludwigshafen, DE
• Jurgen Freidenreich · Schriesheim, DE

Key dates

• Filing date: Mar 17, 1995
• Grant date: May 11, 1999
• Expiry date: Mar 17, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/42
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Sparingly water-soluble active compounds, for example medicinal substances, are converted into the dissolved (molecularly disperse) state by dissolving them in a hydrophilic peptide having a molecular weight above 100 D, for example gelatin. The solubility both during storage and during use of the formulation by the user or patient is thereby ensured, without organic solvents or solubilizing agents which cause undesirable side effects being required.