Method of promoting dermal wound healing with chitosan and heparin or heparin sulfate
US5902798A · kind A · utility
20Cited by
8References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 31, 1996 |
| Grant date | May 11, 1999 |
| Priority date | — |
| Expiry date | Dec 31, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a method for promoting the healing of dermal wounds by applying a composition containing chitosan and the polysaccharide, heparin or heparan sulfate. Heparin or heparan sulfate can be immobilized to chitosan by ionic or covalent bonds, and the degree of N-acetylation of chitosan can range from 25% to 90%. The composition can include a cellulose derivative as an additional polysaccharide to increase the viscosity of the composition. The combination of chitosan and polysaccharide, when applied to a wound site, effectively stimulates and accelerates wound healing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.