Benzimidazole compounds, pharmaceutical compositions containing the compounds and their use
US5902813A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Jan 28, 1998 |
| Grant date | May 11, 1999 |
| Priority date | — |
| Expiry date | Jan 28, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present patent application discloses compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof or an oxide thereof wherein R.sub.3 is ##STR2## wherein A, B and D each is CH, or one or two of A, B and D is N and the others are CH; PA1 R.sup.11 is phenyl, benzimidazolyl, or monocyclic heteroaryl all of which may be substituted one or more times with substituents selected from alkyl, halogen, CF.sub.3, amino, nitro, cyano, acylamino, alkoxy, acyl, phenyl, and monocyclic heteroaryl, and PA1 one of R.sup.6 and R.sup.7 is hydrogen and the other is pyrrolyl which may be substituted one or more times with substituents selected from halohen, alkyl, phenyl, and alkoxy. The compounds are useful for the treatment of various central nervous system disorders such as epilepsy and other convulsive disorders, anxiety, sleep disorders and memory disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.