Synthesis of 6.alpha.-functionalized estriol haptens and protein conjugates thereof
US5902888A · kind A · utility
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5Claims
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Key dates
| Filing date | Nov 14, 1997 |
| Grant date | May 11, 1999 |
| Priority date | — |
| Expiry date | Nov 14, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/926
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are 6.alpha.-derivatized estriol compounds which, when conjugated to a protein, are useful in the in vivo preparation of antibodies specific to estriol. When labeled with a detectable label, the estriol derivatives are useful as haptens in a competitive immunoassay for estriol which demonstrate superior sensitivity with respect to estriol specific antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.