Particles based on polyamino acid(s) and capable of being used as delivery vehicles for active principle(s) and method for preparing them
US5904936A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 25, 1996 |
| Grant date | May 18, 1999 |
| Priority date | — |
| Expiry date | Mar 25, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/412
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to delivery vehicles which are useful for the administration of active principles (APs), preferably medicinal or nutritional active principles, in particular via the oral or parenteral route. The technical problem solved by the invention is that which consists in providing delivery vehicles composed of (nano)- or (micro)particles based on polyamino acids, and which are invert with respect to the AP (proteins), of controllable particle size, strong and inexpensive. According to the invention, the particles have an average size of less than 200 .mu.m and consist of a polyamino acid of the Leu/Glu type, in which Leu/Glu+Leu.gtoreq.3% and the M.sub.w .gtoreq.4,000 D.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.