Process for preparing and cultivating hematopoietic progenitor cells

US5905041A · kind A · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Hartmut Beug · Wien, AT
• Oliver Wessely · Cleveland Heights, US
• Peter Steinlein · Wien, AT
• Eva Deiner · Wien, AT
• Maartje Marie von Lindern · Wien, AT

Key dates

• Filing date: Apr 29, 1996
• Grant date: May 18, 1999
• Expiry date: Apr 29, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2501/392
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Process for the in vitro production of non-immortalised haematopoietic progenitor cells of the erythroid lineage, in which a population of erythroid progenitor cells is exposed to a combination of growth factors containing a glucocorticoid and an oestrogen and at least one ligand of a tyrosine kinase receptor at least until the cells begin to renew themselves.