Passivated porous polymer supports and methods for the preparation and use of same
US5906734A · kind A · utility
53Cited by
41References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 19, 1997 |
| Grant date | May 25, 1999 |
| Priority date | — |
| Expiry date | May 19, 2017 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2220/58
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
This invention relates generally to modified porous solid supports and processes for the preparation and use of same. In particular, passivated porous supports are disclosed which are characterized by a reversible high sorptive capacity substantially unaccompanied by non-specific adsorption of or interaction with biomolecules. Passivation is achieved by use of a passivation mixture comprising a main monomer, a passivating agent comprising polyethyleneimine, and a crosslinking agent, which mixture upon polymerization results in the substantial elimination of the undesirable non-specific interaction with biomolecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.