Formulations and uses thereof in the prevention and treatment of oral lesions
US5906810A · kind A · utility
Inventor
Key dates
| Filing date | Jul 30, 1996 |
| Grant date | May 25, 1999 |
| Priority date | — |
| Expiry date | Jul 30, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K33/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions in the form of solutions, tablets and gels adapted for prophylaxis and treatment of oral lesions. The compositions are suitable for use as an oral lavage, and comprises water, a peroxide (preferably hydrogen peroxide) in a premixed aqueous form in the preparation mixture, with between about 0.01% and about 0.4% of a bicarbonate (preferably sodium bicarbonate). To produce such a composition adapted for the prophylaxis and treatment of oral lesions most preferably involves dissolving the peroxide and bicarbonate in an aqueous solution to produce a premixed preparation. In preferred embodiments, the aqueous solution has between about 0.01% and about 0.8% hydrogen or benzoyl peroxide and between about 0.01% and about 0.4% sodium bicarbonate. In more preferable embodiments of the present invention, the oral lavage (formulation) includes hydrogen peroxide at a concentration of about 0.4% and sodium bicarbonate at a concentration of about 0.2%. Additionally, a method for prophylaxis and treatment of oral lesions incident the use of chemotherapeutic agents is included in the present invention. This method involves the step of initially providing …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.