Process for producing L-glutamic acid by fermentation with E. coli resistant to aspartic acid antimetabolite
US5908768A · kind A · utility
21Cited by
2References
12Claims
0Family size
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Key dates
| Filing date | Apr 23, 1997 |
| Grant date | Jun 1, 1999 |
| Priority date | — |
| Expiry date | Apr 23, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/849
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A fermentative process for producing L-glutamic acid efficiently and at low cost is disclosed. Also disclosed are microorganisms having improved ability to produce L-glutamic acid. These microorganisms belong to the genus Escherichia, have resistance to an aspartic acid antimetabolite, and are deficient in .alpha.-ketoglutaric acid dehydrogenase activity. The process comprises cultivating one of these microorganisms in a liquid medium, accumulating L-glutamic acid in the culture medium, and collecting L-glutamic acid. In particular, E. coli AF13199 (FERM BP-5807).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.