Process for preparing butanone derivatives
US5908770A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 14, 1997 |
| Grant date | Jun 1, 1999 |
| Priority date | — |
| Expiry date | Jul 14, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/22
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for the preparation of a saturated butanone having a terminal substituted aryl group (I) by the selective reduction of an aryl-substituted .alpha.,.beta.-unsaturated butanone (II) is presented. The aryl moiety can be mono- or polysubstituted by one or more C.sub.1 -C.sub.6 alkoxy, methylenedioxy or hydroxyl radicals and R is a C.sub.1 -C.sub.6 radical. The .alpha.,.beta.-unsaturated butanone (II) is subjected to the action of the enzymes of a yeast or of a filamentous fungus to give a mixture of (I) and an alcohol (III). (I) and (III) are isolated and purified. (III) can be enzymatically oxidized to provide (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.