Patent · US Expired

Process for preparing butanone derivatives

US5908770A · kind A · utility

4Cited by
1References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 14, 1997
Grant dateJun 1, 1999
Priority date
Expiry dateJul 14, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P7/22
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A process for the preparation of a saturated butanone having a terminal substituted aryl group (I) by the selective reduction of an aryl-substituted .alpha.,.beta.-unsaturated butanone (II) is presented. The aryl moiety can be mono- or polysubstituted by one or more C.sub.1 -C.sub.6 alkoxy, methylenedioxy or hydroxyl radicals and R is a C.sub.1 -C.sub.6 radical. The .alpha.,.beta.-unsaturated butanone (II) is subjected to the action of the enzymes of a yeast or of a filamentous fungus to give a mixture of (I) and an alcohol (III). (I) and (III) are isolated and purified. (III) can be enzymatically oxidized to provide (I).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.