Patent · US Expired

Nitrile hydratase

US5910432A · kind A · utility

5Cited by
1References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 15, 1997
Grant dateJun 8, 1999
Priority date
Expiry dateDec 15, 2017

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/822
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention provides the amino acid sequence and base sequence of a Pseudonocardia thermophila-derived nitrile hydratase, provides further a method for changing its amino acid sequence and base sequence without substantially changing the functions of said nitrile hydratase, and nitrile hydratases having a base sequence and an amino acid sequence as changed on the basis of said method, and provides furthermore a recombinant plasmid having the gene of said nitrile hydratase, a transformant containing said recombinant plasmid, a method of using said transformant for producing said enzyme, and a method of using said transformant for producing the corresponding amide compound from a nitrile compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.