Monomeric and dimeric antibody-fragment fusion proteins
US5910573A · kind A · utility
82Cited by
1References
19Claims
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Key dates
| Filing date | Jul 22, 1994 |
| Grant date | Jun 8, 1999 |
| Priority date | — |
| Expiry date | Jul 22, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/73
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes a new class of antigen binding molecules which contain Fv-fragments of an antibody but do not use the constant antibody domains. They can also dimerize with other antibody fragment molecules or with non-antibody fragment molecules to form bi- or multifunctional antibody-fragment fusion proteins and so-called miniantibodies, respectively. The new fusion proteins can be used in the broad field of diagnostic and therapeutical medicine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.