Patent · US Expired

Polypeptides of glycosaminoglycan sulfotransferase originating from human and DNA coding for the polypeptides

US5910581A · kind A · utility

2Cited by
0References
7Claims
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Key dates

Filing dateJul 24, 1997
Grant dateJun 8, 1999
Priority date
Expiry dateJul 24, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A polypeptide of glycosaminoglycan sulfotransferase originating from human and having the following physical and chemical properties: PA1 (i) action: sulfate group is transferred from a sulfate group donor to N-acetylgalactosamine residue or galactose residue of glycosaminoglycan; PA1 (ii) substrate specificity: sulfate group is transferred to the hydroxyl group position at C-6 of N-acetylgalactosamine residue of chondroitin; and sulfate group is transferred to the hydroxyl group position at C-6 of galactose residue of keratan sulfate; and PA1 (iii) molecular weight: about from 50,000 to 55,000 Da.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.