Detecting abnormal reactions in a red blood cell agglutination
US5911000A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Aug 1, 1997 |
| Grant date | Jun 8, 1999 |
| Priority date | — |
| Expiry date | Aug 1, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/381
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Abnormal reactions in a red blood cell classification by agglutination, are checked following centrifugation of a sample in a column of a cassette, the column containing microparticles. This is done by imaging the column on a detector array that is used to correlate the images with predefined red cell classes based upon the distribution of the images across the column. However, prior to the correlation step, abnormal reactions are checked for by detecting whether any of the following is present: PA1 i) errors that cause imaged features of the column or any pellet produced therein to be out of range; PA1 ii) hemolysis of the sample; PA1 iii) insufficient or too many blood cells present; PA1 iv) mixed field agglutination; and PA1 v) presence of fibrin at the top of the microparticles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.