Human Homolog of the rat G protein gamma-5 subunit
US5912130A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 7, 1998 |
| Grant date | Jun 15, 1999 |
| Priority date | — |
| Expiry date | Jul 7, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a nucleic acid sequence which identifies and encodes a G protein gamma subunit (gpg) which was isolated from human pituitary gland. The invention provides for genetically engineered expression vectors and host cells comprising nucleic acid sequence encoding GPG and for gpg antisense molecules. The invention also provides for purified GPG; antibodies, antagonists and inhibitors which specifically bind GPG; and pharmaceutical compositions and methods of treatment based on GPG antagonists and inhibitors. The invention provides for diagnostic assays which utilize diagnostic compositions comprising nucleic acid sequences, or complements thereof, encoding GPG, purified GPG to be used as a positive control, and antibodies which specifically bind to GPG.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.