Method for chromosome classification by decorrelaiton statistical analysis and hardware therefore
US5912165A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 1, 1997 |
| Grant date | Jun 15, 1999 |
| Priority date | — |
| Expiry date | Oct 1, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6417
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and hardware for chromosome classification by decorrelation statistical analysis to provide color (spectral) karyotypes and to detect chromosomal aberrations. The method and hardware employ a set of N decorrelation matched filters for chromosome classification. The N decorrelation matched filters are dedicated for extracting decorrelated spectral data from chromosome samples painted according to a specific experimental protocol. The N decorrelation matched filters being described by: ##EQU1## where V.sub.ik min equals minimum V.sub.ik over all i, and V.sub.ik max equals maximum V.sub.ik over all i, and wherein N is an integer greater than two.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.