Heteroatoms-containing tricyclic compounds
US5912238A · kind A · utility
1Cited by
6References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 18, 1994 |
| Grant date | Jun 15, 1999 |
| Priority date | — |
| Expiry date | Jul 18, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/01
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns the compounds of formula I ##STR1## wherein the substituents have various significances. They are prepared by several processes including epimerizing replacement, treatment with cyanogen bromide or thiophosgene, treatment with an acid having a non-nucleophilic anion, treatment with dimethylsulfoxide and acetic anhydride, acylation, treatment with an oxalyl derivative and ammonia, methylation, oxidation, deprotection and protection. They possess interesting pharmacological activity as antiinflammatory, immunosuppressant, antiproliferative and chemotherapeutic drug resistance reversing agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.