Compounds having effects on serotonin-related systems
US5912256A · kind A · utility
9Cited by
4References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 22, 1997 |
| Grant date | Jun 15, 1999 |
| Priority date | — |
| Expiry date | May 22, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/454
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A series of 1-(4-indolyloxy)-3-(4-hydroxy-4-naphthylpiperidin-1-yl)propanes are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1.sub.A receptor, yet lack mutagenic potential as measured by assays of chromosomal aberration. The compounds are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal, and for the treatment of depression and other conditions for which serotonin reuptake inhibitors are used.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.