Method of purifying chemokines from inclusion bodies
US5912327A · kind A · utility
26Cited by
3References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 20, 1997 |
| Grant date | Jun 15, 1999 |
| Priority date | — |
| Expiry date | Mar 20, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to processes for the purification of proteins. More specifically, methods for solubilizing and purifying proteins expressed in an insoluble form using low concentrations of chaotropic agents, such as guanidine salts, are provided. Also provided are methods for refolding proteins solubilized according to the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.