Chiral synthesis of tertiary alcohols with a hydrolase
US5912355A · kind A · utility
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10Claims
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Key dates
| Filing date | Nov 12, 1997 |
| Grant date | Jun 15, 1999 |
| Priority date | — |
| Expiry date | Nov 12, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/004
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Method of preparing an optically active compound of formula, wherein R and R.sup.1 are independently alkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, cycloalkyl, aryl, aralkyl, a heterocyclic group or a C.sub.1 -C.sub.4 alkyl-heterocycle, each being optionally substituted, procided that R and R.sup.1 are not identical and * is an optically active chiral center, from the corresponding racemic ester or diol by treating with a hydrolase enzyme.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.