Production of a multimeric protein by cell fusion method
US5916771A · kind A · utility
388Cited by
7References
11Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 11, 1996 |
| Grant date | Jun 29, 1999 |
| Priority date | — |
| Expiry date | Oct 11, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention features a method of producing a multimeric protein from a hybrid cell formed from the fusion of two or more cells, each of which cell is engineered to express one component of the multimeric protein, as well as a method for screening for successful fusion of the cells to produce a desired hybrid cell. The methods of the invention are widely applicable to the production of proteins having two or more components.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.