Patent · US Expired

2-fluoro-9-trimethylsilyladenine

US5917040A · kind A · utility

1Cited by
10References
1Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 20, 1993
Grant dateJun 29, 1999
Priority date
Expiry dateMay 20, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H19/16
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A process for the preparation of 2-fluoro-9- (2,3,5-tri-O-benzyl-beta-D-arabinofuranosyl)adenine (I) is described. The process involves reacting a protected 2-fluoro adenine with a protected chlorosugar under controlled conditions of temperature (80-85.degree. C.) to produce (I), rather than using a process involving fluorinating a 2-substituted nucleoside precursor of (I).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.