Non-antigenic branched polymer conjugates
US5919455A · kind A · utility
257Cited by
27References
40Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 20, 1997 |
| Grant date | Jul 6, 1999 |
| Priority date | — |
| Expiry date | Mar 20, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G65/338
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with the polymers and biologically active molecules such as proteins and peptides demonstrate extended circulating life in vivo. Substantially fewer sites on the biologically active material are used as attachment sites. Methods of forming the polymer, conjugating the polymers with biologically active moieties and methods of using the conjugates are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.