Liposomal influenza vaccine composition and method

US5919480A · kind A · utility

Assignee

• YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. · IL

Inventors

• Eliezer Kedar · Jerusalem, IL
• Ilan Babai · Netanya, IL
• Yechezkel Barenholz · Jerusalem, IL

Key dates

• Filing date: Jun 23, 1997
• Grant date: Jul 6, 1999
• Expiry date: Jun 23, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S436/829
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Subunit influenza vaccines containing an influenza H/N antigen and a cytokine immunopotentiator, where at least one and preferably both are encapsulated in liposomes, are described. The vaccines stimulate a strong humoral and CTL response. Also described are methods of immunization using such vaccines.