Substituted aminoquinolines as modulators of chemokine receptor activity
US5919776A · kind A · utility
69Cited by
2References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 18, 1997 |
| Grant date | Jul 6, 1999 |
| Priority date | — |
| Expiry date | Dec 18, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/4706
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to aminoquinolines of Formula I: ##STR1## (wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3, and/or CXCR-4.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.