Formulations and methods of reducing toxicity of antineoplastic agents
US5919816A · kind A · utility
48Cited by
1References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 17, 1997 |
| Grant date | Jul 6, 1999 |
| Priority date | — |
| Expiry date | Oct 17, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides for pharmaceutical formulations of compounds which are useful as protective agents when administered to patients also receiving antineoplastic drugs. The invention also includes methods of reducing the toxicity of various antineoplastic agents by administering an effective amount of the protective agent to a patient receiving one or more antineoplastic agents. The compounds useful as protective agents have either a sulfhydryl moiety or are reducible disulfides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.