Patent · US Expired

Mammalian IAP antibodies and diagnostic kits

US5919912A · kind A · utility

20Cited by
0References
26Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 4, 1995
Grant dateJul 6, 1999
Priority date
Expiry dateAug 4, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/975
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and primers and probes for the identification and isolation of additional IAP genes. In addition, methods for treating diseases and disorders involving apoptosis are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.