Metal oxide matrix biosensors
US5922183A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 23, 1997 |
| Grant date | Jul 13, 1999 |
| Priority date | — |
| Expiry date | Jun 23, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/817
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A thin film matrix for biomolecules, suitable for forming electrochemical and biosensors comprising a general class of materials known as hydrous metal oxides which are also conductive or semiconductive of electrons and which have been shown to have excellent stability against dissolution or irreversible reaction in aqueous and nonaqueous solutions. The composites are bifunctional, providing both amperometric and potentiometric (pH) transduction. The thin film composites of the oxides and biological molecules such as enzymes, antibodies, antigens and DNA strands can be used for both amperometric and potentiometric sensing. Hydrous Ir oxide is the preferred matrix embodiment, but conducting or semiconducting oxides, of Ru, Pd, Pt, Zr, Ti and Rh and mixtures thereof have similar features. The hydrous oxides are very stable against oxidation damage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.